吴德群副教授
发布时间: 2015-01-14

个人简介

  • 2004 -2009 武汉大学硕博连读理学博士
  • 2009 新加坡南洋理工大学博士后
  • 2010-2013美国康奈尔大学博士后
  • 2013- 东华大学纺织学院副教授

研究方向

  1. 生物医用纺织
  2. 材料天然纤维改性
  3. 生物可降解材料自组装及其药物缓释载体
  4. 纳米生物传感器

荣誉及获奖情况

  • 2014上海市浦江人才计划
  • 2014纺织工业联合会科学技术进步一等奖

近五年承担的科研项目

  2014年上海市浦江人才计划

近五年代表性论文、专利

代表性论文:

  1. Wu DQ, Sun YX, Xu XD, Cheng SX, ZhangXZ, and Zhuo RX. Biodegradable and pH-sensitive hydrogels for cell encapsulation and controlled drug release. Biomacromolecules 2008,9:1155-1162.
  2. Wu DQ, Wang T, Lu B, Xu XD, Cheng SX, Jiang XJ, ZhangXZ, Ren-Xi Zhuo. Fabrication of supramolecular hydrogels for drug delivery and stem cell encapsulation. Langmuir 2008,24:10306-10312.
  3. Wu DQ, Lu B, Chang C, Chen CS, Zhang YY, Cheng SX, Zhang XZ, Zhuo RX. Galactosylated fluorescent labeled micelles as a liver targeting drug carrier. Biomaterials. 2009,30:1363-1371.
  4. Wu DQ, Qiu F, Wang T, Zhang XZ, Zhuo RX. Towards development of partially biodegradable and injectable thermoresponsive hydrogels for potential biomedical applications. ACS Applied materials & interfaces. 2009,1:319-327.
  5. Wu DQ, Li ZY, Fan JJ, Cheng SX, Jiang XJ, ZhangXZ, Ren-Xi Zhuo. Porphyrin and Galactosyl Conjugated Micelles for Targeting Photodynamic Therapy. Pharmaceutical Research, 2010, 27:187-199.
  6. Dequn Wu, Jun Wu, Chi-Chang Chu. A Novel Family of Biodegradable HybridHydrogels from Arginine-based Poly(ester amide) and Hyaluronic AcidPrecursors. Soft matter. 2013, DOI: 10.1039/c3sm27820d.
  7. Jun Wu, Dequn Wu, Martha A. Mutschler, and Chih-Chang Chu, Cationic Hybrid Hydrogels from Amino Acid-Based Poly (ester amide): Fabrication, Characterization, and Biological Property.Advanced Functional Materials. 2012,22,3815-3823.
  8. Xiao-Hong Qin, De-Qun Wu, Chih-Chang Chu. Dual functions of polyvinyl alcohol (PVA): fabricating particles and electrospinningnanofibers applied incontrolled drug release. Journal of Nanoparticle Research. 2013,15:1395-1409.
  9. Lu B,Wu DQ,Zheng H,Quan CY,Zhang XZ, Zhuo RX.Galactosyl conjugated N-succinyl-chitosan-graft-polyethylenimine for targeting gene transfer.Molecular Biosystems, 2010, 6, 2529-2538.
  10. Xun W, Wu DQ, Li ZY, Wang HY, Huang FW, Cheng SX, Zhang XZ, ZhuoRX.Peptide-Functionalized Thermo-Sensitive Hydrogels for Sustained Drug Delivery. Macromolecular bioscience. 2009, 12, 1219-1226.
  11. Quan CY, Wu DQ, Chang C, Zhang GB, ChengSX, Zhang XZ, Zhuo RX. Synthesis of thermo-sensitive micellar aggregates self-assembled from biotinylated PNAS-b-PNIPAAm-b-PCL triblock copolymers for tumor targeting. Journal of Physical Chemistry C. 2009, 113:11262-11267.
  12. Wang T, Wu DQ, Jiang XJ, Li XY, Zhang JF, Zheng ZB, Jiang H, Huang CX, Zhang XZ. Novel thermosensitive hydrogel injection inhibits post-infarct ventricle remodeling. European Journal of Heart Failure. 2009, 11:14-19.
  13. Lu B, Wang CF, Wu DQ, Li C, Zhang XZ, Zhuo RX. Chitosan based oligoamine polymers:synthesis, characterization, and gene delivery. Journal of Controlled Release. 2009,137:54-62
  14. Hu CH, Zhang L, Wu DQ, Cheng SX , Zhang XZ, Zhuo RX. Heparin-modified PEI encapsulated in thermosensitive hydrogels for efficient gene delivery and expression. Journal of materials chemistry. 2009,19:3189-3197.
  15. Qin XH, Wu DQ. Effect of different solvents on poly(caprolactone) (PCL)electrospun nonwoven membranes. Journal of Thermal Analysis andCalorimetry, 2011, 102, 1-7.
  16. Chang C, Wei H, Feng J, Wang ZC, Wu XJ, Wu DQ, Cheng SX, Zhang XZ, and ZhuoRX.Temperature and pH Double Responsive Hybrid Cross-Linked Micelles Based on P(NIPAAm-co-MPMA)-b-P(DEA): RAFT Synthesis and “Schizophrenic” Micellization. Macromolecules 2009,42:4838-4844.
  17. Zhang J, Xu XD, Wu DQ, Zhang XZ, Zhuo RX. Synthesis of thermosensitiveP(NIPAAm-co-HEMA)/cellulose hydrogels via “click” chemistry. Carbohydrate Polymers. 2009,77:583–589.
  18. Qiu F, Feng J, Wu DQ, Zhang XZ, Zhuo RX. Nanosized Micelles Self-Assembled from amphiphilic dextran-graft-methoxypolyethylene glycol/poly(epsilon-caprolactone) copolymers. European Polymer Journal. 2009, 45:1024-1031.
  19. Wang T, Jiang XJ, Tang QZ, Li XY, Lin T, Wu DQ, Zhang XZ, Okello E. Bone marrow stem cells implantation with a-cyclodextrin/MPEG–PCL–MPEG hydrogel improves cardiac function after myocardial infarction. ActaBiomaterialia. 2009, 5: 2939-2944.
  20. Wei H, Wu DQ, Li Q, Cheng SX, ZhangXZ, and Zhuo RX. Preparation of shell cross-linked thermoresponsive hybrid micelles as well as hollow spheres based on P(NIPAAm-co-HMAAm-co-MPMA)-b-PCL. Journal of physical chemistry C. 2008, 112:15329.
  21. Qin XH, Wu DQ. Effect of different solvents on poly(caprolactone) (PCL)electrospun nonwoven membranes. Journal of Thermal Analysis andCalorimetry, 2011, 102, 1-7.
  22. Li XY, Wang T, Jiang XJ, Lin T, Wu DQ, Zhang XZ. Injectable Hydrogel Helps Bone Marrow-Derived Mononuclear Cells Restore Infarcted Myocardium. Cardiology. 2010, 115,194-199.
  23. Wang T, Jiang XJ, Tang QZ, Li XY, Lin T, Wu DQ, Zhang XZ, Okello E. Bone marrow stem cells implantation with a-cyclodextrin/MPEG–PCL–MPEG hydrogel improves cardiac function after myocardial infarction. ActaBiomaterialia. 2009, 5: 2939-2944.
  24. Jun Wu, Xin Zhao, Dequn Wu and Chih-Chang Chu.Development of a biocompatible and biodegradable hybrid hydrogel platform for sustained release of ionic drugs. J. Mater. Chem. B, 2014,2, 6660-6668.

专利:

  1. 张先正,吴德群,卓仁喜。温度敏感性生物可降解水凝胶的制备与应用。专利号:200810048486.0
  2. Chu Chih-Chang, Wu De-Qun. Advanced Generation Lysine-based Multifunctional Poly(ester amide)s. D-5447
  3. Chu Chih-Chang, Wu De-Qun. Peptide-based Poly(ester amide)s D-5400
  4. Chu Chih-Chang, Wu De-Qun, He Mingyu. Polysaccharide-based hydrogels and hybrid hydrogels and precursors thereof, methods of making same, and uses thereof. Publication number: WO2013/181566
  5. Chu Chih-Chang, Qin Xiao-Hong, Wu De-Qun. Fabrication of Synthetic Biodegradable Amino Acid Poly(ester amide)s Nanoparticles . D-5597

联系信息

电话:6779-2380

电子邮箱:dqwu@dhu.edu.cn