关国平副教授
发布时间: 2015-02-10

个人简介

        关国平,男,19808月,工学博士,副教授。英国Textile Institute、中国生物材料学会/上海市生物医学工程学会会员。Textile Research JournalFibers and PolymersIEEE 国际学术会议审稿人。主要研究方向为生物医用纺织材料及医用材料的生物学评价。

主讲及参与课程

  • 生物学及医学基础
  • 生物医用纺织品
  • 纺织生物医用材料与技术
  • 纺织生物医用材料成型与评价
  • 组织工程学
  • 专业前沿课

学习及工作经历

  • 2012.9至今,东华大学,副教授;
  • 2011.9-2012.8,东华大学,讲师;
  • 2009.9-2011.8,东华大学博士后,研究方向为纺织基小口径人造血管的制备与评价;
  • 2006.9-2009.6,苏州大学,获纺织工程工学博士学位,研究方向为丝蛋白基生物材料;
  • 2003.9-2006.6,西南大学,获细胞生物学理学硕士学位;
  • 1999.9-2003.6,西南农业大学,获动物医学农学学士学位;

研究方向

  1. 生物医用材料的设计与制备;
  2. 医用材料的生物学评价;
  3. 生物材料表面及界面分析、改性及细胞与分子机制的探索;

近年来承担的科研项目

  • 主持2011年国家自然科学基金青年基金资助1项,抗血栓及促内皮化混构小口径人造血管研究,项目编号:5100301419万,2011.1-2013.12
  • 主持2011年东华大学中央高校基本科研业务费(追加)专项基金重点项目1项,仿真环境下丝涤小口径人造血管与血管内皮细胞相互作用机制研究,项目编号:2011D1180118, 30万,2011.10-2012.10;
  • 主持中国博士后科学基金面上项目资助1项,3 万,编号:20100480570
  • 主持东华大学青年教师科研启动基金项目1项,具抗凝血及促内皮化双功能小径人造血管的制备,2009.10-2011.09, 2, 项目编号:101-10-0044019;
  • 主持纺织面料教育部重点实验室开放课题1项,丝涤混构小径管状织物的成型及其结构调控,1.5万,2011.10-2012-10项目编号:P1103;
  • 指导上海市大学生创新计划课题1项,丝素纤维-PET小径人造血管的制备及其抗凝血性能研究,王银雁,王宇骅,何南霏等,2009.4-2011.42万;
  • 指导上海市大学生创新计划课题1项,真丝含量及分布对丝涤混构小口径人造血管性能影响,胡星友,曾水林,张露莹等,2011.6-2013.62万;
  • 指导上海市大学生创新计划课题1项,人造血管水渗透性测试方法的标准化细节探索,徐睿,王义斌,何欣煜 等,2012.6-2014.62万;
  • 作为主要研究人员申请并参与2010年上海市科学技术委员会非政府间国际合作项目1项,辅助体内血管原位再生的纤维集合体小径人造血管,2010.7 -2012.715万,项目编号:10520706600
  • 作为主要研究人员申请并参与2010年博士点基金(博导类)1项,项目编号:20100075110001 6万,2011.1-2013.12;
  • 作为主要研究人员申请并参与多层贯穿三维仿真结构的小口径人造血管设计与成型,东华大学纺织生物医用材料科学与技术创新引智基地2010年重点项目("111"计划)资助,2010.09-2011.0815万,项目编号:B07024-SP1007
  • 家蚕细胞系的建立、筛选、鉴定及应用,“863”项目,项目编号:2004AA2Z1020;主要承担细胞系的建立与鉴定;
  • 家蚕细胞系的建立、筛选、鉴定及应用,国家自然科学基金项目,项目编号:30471312;主要承担细胞系的建立与鉴定;
  • 家蚕主要经济性状功能基因组与分子改良研究,国家重点基础研究发展计划课题(“973”课题),项目编号:2005CB121000;主要承担细胞系的建立与鉴定、基因的克隆与功能分析;

发表论著

论文

  1. M. Fazley ELAHI, Guoping GUAN and Lu WANG. Improved Hemocompatibility of Silk Fibroin Fabric Using Layer-by-Layer Polyelectrolyte Deposition and Heparin Immobilization. J. App. Polym. Sci. 2014, 131,40772 (SCI)2014.4.14 DOI: 10.1002/app.40772
  2. M. Fazley ELAHI, Guoping GUAN and Lu WANG. Influence of layer-by-layer polyelectrolyte deposition and EDC/NHS activated heparin immobilization onto silk fibroin fabric. Materials. 2014, 7(4), 2956-2977 (SCI) 收录号000336091400028
  3. M. Fazley ELAHI, Guoping GUAN and Lu WANG. Hemocompatibility of surface modified silk fibroin materials: a review. Reviews on Advnanced Materials Science Journal. Reviews on Advnanced Materials Science Journal. 2014 (38) :148-159(SCI)2011年影响因子0.9152014.2.18 Vol38N2 Oct Rev. Adv. Mater. Sci.
  4. 关颖,关国平,杨小元,彭蕾,王璐,丝涤混构小口径人造血管的实验研究(一)——设计与成型,东华大学学报,2014
  5. 关颖,关国平,杨小元,彭蕾,王璐,丝涤混构小口径人造血管的实验研究(二)——结构与性能,东华大学学报,2014
  6. 陈肖会,关国平,王璐,环氧化合物交联明胶水凝胶的制备及表征,生物医学工程学进展,2014, 35(1) :18-22
  7. 关国平,关红涛,王璐,韧带损伤及人工韧带应用与研究进展,生物医学工程学进展,2013344):234-238.
  8. GUAN Guo-ping(关国平),Md. Fazley Elahi, WANG Lu(), SHEN Gao-tian(沈高天), CHEN Xiao-hui(陈肖会), ZHOU Hao(周浩), XU Rui(徐睿), Promoted Cytocompatibility of Silk Fibroin Fiber Vascular Graft through Chemical Grafting with Bioactive Molecules, Journal of Donghua University ( Eng. Ed. ) Vol. 30, No. 5 (2013) :362-366(EI)
  9. YANG Xiao-yuan(杨小元), WANG Lu(), GUAN Guo-ping(关国平), GUAN Ying(关颖), KING W Martin. Preparation and mechanical performance of blended polyester/silk small diameter arterial prostheses. Journal of Donghua University ( Eng. Ed. ) Vol. 30, No. 5 (2013) :356-358(EI)
  10. Guoping Guan, Lu Wang, Mingzhong Li and Lun Bai, In vivo biodegradation of porous silk fibroin films implanted beneath the skin and muscle of the rat, Bio-Medical Materials and Engineering 24 (2014) 789–797(SCI)
  11. 高洪泉,李学敏,吴彩琴,关国平,王富军,王璐,王克强,张红旗,猪动脉及心脏瓣膜内皮细胞的形态学特征,解剖学报,2013444):541-546
  12. 李学敏,潘天岳,王璐,关国平,王克强,杨琳,张红旗,猪颈总动脉有形成分与血管顺应性的关系,复旦学报(医学版),2013404):413-418
  13. Elahi MF, Lu W, Guoping G, Khan F (2013) Core-shell Fibers for biomedical Applications-A Review. J Bioengineer & Biomedical Sci 3: 121. doi:10.4172/2155-9538.1000121
  14. Xiaoyuan Yang, Lu Wang*, Guoping Guan, Martin W. King, Yuling Li, Lei Peng, Ying Guan, Xingyou Hu. Preparation and evaluation of bicomponent and homogeneous polyester silk small diameter arterial prostheses. Journal of Biomaterials Applications. 2014, Vol 28(5) 676687 DOI: 10.1177/0885328212472216 (SCI, 二区)
  15. YANG Xiaoyuan, WANG Lu, GUAN Guoping, et al. What is the Optimum Cover Factor? Applied Mechanics and Materials. 2013(302), 292-297. (EI 收录)
  16. YANG Xiao-yuan, WANG Lu, GUAN Guo-ping, Peng Lei et al, Fabrication and mechanical evaluation of woven silk-polyester blended small diameter prototype arterial prostheses, 2012 International Forum on Biomedical Textile Materials. 216-220, 2012 (ISTP).
  17. Peng Lei, WANG Lu, GUAN Guo-ping, YANG Xiao-yuan et al, Degumming of woven silk/polyester prototype vascular graft, 2012 International Forum on Biomedical Textile Materials. 185-190, 2012 (ISTP).
  18. YANG Xiao-yuan, GUAN Guo-ping, WANG Lu, Peng Lei, WANG Yin-yan, WANG Yu-hua, ZHAN Quan, LI Yu-ling, Martin W KING, Preparation and Evaluation of Prototype of Woven Small-caliber Artificial Blood Vessels, 2011 International Forum on Biomedical Textile Materials, 2011:433-437(ISTP)
  19. ZHAN Quan, GUAN Guo-ping, YANG Xiao-yuan, PENG Lei, WANG Qi, WANG Lu, Robert GUIDOIN, Plasma and Ultraviolet Irradiation Initiated Grafting Treatment of PET, 2011 International Forum on Biomedical Textile Materials, 2011:194-200(ISTP)
  20. PENG Lei, GUAN Guo-ping, ZHAN Quan, YANG Xiao-yuan, WANG Lu, ZHOU Hao, Preliminary Study on Heparin-immobilization of Silk Fibroin Fibers. 2011 International Forum on Biomedical Textile Materials, 2011:161-165(ISTP)
  21. DAI Hong-qin(戴宏钦), BAI Lun(白伦), ZHAN Kui-hua(詹葵花), SUN Zi-ling(孙自玲), GUAN Guo-ping(关国平), Computer Simulation of Random Packing of Spherical Particles in Two Dimensions, Journal of Donghua University ( Eng, Ed.) 2011, Vol. 28 (1):31-34(EI)
  22. Guoping Guan, Lun Bai, Baoqi Zuo, Mingzhong Li, Zhengyu Wu, Yonglin Li and Lu Wang, Promoted Dermis Healing from Full-thickness Skin Defect by Porous Silk Fibroin Scaffolds (PSFSs), Bio-Medical Materials and Engineering. 2010(20) :295-308(SCI).
  23. Guoping Guan, Lun Bai, Baoqi Zuo, Mingzhong Li, Zhengyu Wu, Lu Wang, Yonglin Li, Distinct Tissue Responses to Porous Silk Fibroin Scaffolds (PSFSs) and Polyvinyl Alcohol (PVA) Sponges in vivo, IEEE, The 3rd International Conference on BioMedical Engineering and Informatics (BMEI 2010) and the 3rd International Congress on Image and Signal Processing (CISP 2010), 2010(4) :1668-1672 (EI).
  24. Guoping GUAN, Lun BAI, Baoqi ZUO, Mingzhong LI, Zilin SUN, Zhengyu WU, Neovascularization of Porous Silk Fibroin Films (PSFFs) as Dermis Substitutes Implanted in Rats, Materials Science Forum, Vols. 610-613 (2009) pp 1113-1119 (EI).
  25. Guoping Guan, Lun Bai, Baoqi Zuo, Mingzhong Li, Zhengyu Wu, Yonglin Li, Scaffolds Decorated by in vivo Environment Improve Cell Proliferation and Wound Healing, IEEE, The 2nd International Congress on Image and Signal Processing &The 2nd International Conference on BioMedical Engineering and Informatics, 2009(3): 1151-1156 (EI).
  26. Lun Bai, Baoqi Zuo, Guoping Guan, Lixing Dai, Yongzhen Chen, Zhenyu Zhou, Jianmei Xu, Zhenyu Wu: On the Growth Morphous of the Capillaries and Tissue in the Porous Silk Fibroin Films, Front.Mater.Sci.China, 2008, 2(3):266-270. (EI)
  27. Kui-hua Zhan, Lun Bai, Guo-ping Guan and Hong-qin Dai, Characterization of Angiogenesis during Skin Wound Repair by Porous Silk Fibroin Film, Advanced Materials Research, 2011, 175-176:181-185 (EI).
  28. Bai Lun, Xu Jianmei, Sun Qilong, Di Chuanxia, Zuo Baoqi, Guan Guoping, Wu Zhengyu, Density of Capillaries and the Oxygen Diffusion Model in the Porous Silk Fibroin Film, Front. Mater. Sci. China, 2007, 1(3): 237-242. (EI)
  29. Sun ZiLing, Bai Lun, Guan GuoPing, Zhuan KuiHua, Dai HongQin, Protein Adsorption and Biocompatibility of Porous Silk Fiboin Films, IEEE for The 2nd International Congress on Image and Signal Processing & The 2nd International Conference on BioMedical Engineering and Informatics, 2009(3): 1143-1146 (EI).
  30. Kuihua ZHAN, Lun BAI, Hongqin DAI, Guoping GUAN, Ziling SUN, The Models and Oxygen Distribution of Two-dimensional Capillary Network, Proceedings of the 5th China-Japan Conference on Mechatronics 2008, August 23, 2008, Atsugi, Japan (ISTP).
  31. 关国平,潘敏慧,鲁成,一种家蚕卵巢原代细胞制作方法探索,西南农业大学学报,2006, (02): 326-328.
  32. 关国平,潘敏慧,陈敏,鲁成,家蚕胚胎细胞系(BmE-SWU2)同工酶的研究,蚕业科学,2006, (01): 110-113.
  33. 谢敏,关国平,刘辉凤,伍冬平,白伦,血管新生及丝蛋白材料血管化过程,现代生物医学进展, 2009, 9(08): 1551-1554.
  34. 柴春利,钱平,关国平,徐伟,李文学,夏庆友,鲁成,家蚕vasa基因的结构及表达研究,蚕业科学,2006, (04): 469-476.

专利

  1. 一种餐饮行业从业人员专用口罩
  2. 关国平,王俊梅,王璐,付译,具茶几功能的行李箱,中国发明专利,申请号:,申请日期 2014日;
  3. 关国平,沈高天,王璐,王富军,胡星友,徐睿,黄健涛,一种管道器官浇注成型装置及其使用方法,中国发明专利,申请号:201410218617.0,申请日期 2014522日;公开号:CN 103989537,公开日:2014820日;
  4. 关国平,王璐,沈高天,王富军,胡星友,徐睿,黄健涛,管状纤维集合体增强管道器官浇注成型装置及其使用方法,中国发明专利,申请号:201410219839.4,申请日期 2014522日;公开号:CN 103989538,公开日:2014820日;
  5. 关国平,王璐,杨小元,湛权,李毓陵,彭蕾,周浩,王银雁,一种三层机织小口径人造血管及其制备方法,中国发明专利,申请号:201110142604.6,申请日期 2011530日;公开号:CN102212918A,公开日: 20111012日;专利号 ZL 2011 1 0142604.6
  6. 杨小元,关国平,周浩,王宇骅,何南霏,王璐,一种变速式水平给纱机,中国实用新型,授权专利号:ZL 2011 2 0177639.9,授权日期:201221日;
  7. 杨小元,王璐,周浩,关国平等,一种一体成型三层机织仿真人造血管,中国发明专利,授权专利号:ZL 2011 1 0142605.0,授权日期:20121107日;
  8. 王璐,沈高天,林婧,关国平,王富军,金马汀,人造血管体外模拟弯折疲劳老化装置及其测试方法,中国发明专利,专利号:ZL 2011 1 0049112.2,申请日期:201131日。授权公告日:201343;
  9. 王璐,陈方,王文祖,尚亚峰,邹婷,王富军,周君梅,谢华,关国平等,一种可逐步降解的编织型输尿管支架管及其制备方法. 发明专利申请号:201110241408.4,申请日期:20118月。专利号:ZL 2011 1 0241408.4 授权公告日:20140416
  10. 王璐,刘冰,林婧,王富军,关国平,金马汀. 腔内隔绝术用人造血管扭转疲劳模拟装置及其测试方法,授权专利号:ZL 201210001843.4,发明专利申请号201210001843.4,申请日期:20111 5日,申请人:东华大学,公开号:102564877A,公开日: 2012711日;
  11. 林婧,王璐,付译,王富军,关国平,管晓宁,宋戈,杜佳,陈基扬. 微创血管支架扭转弯折疲劳模拟装置及其测试方法,发明专利申请号:201210546550.4 ,申请日期:20121214日,申请人:东华大学;
  12. 王璐,杨小元,李毓陵,关国平,关颖. 一种机织人造血管的制备方法,发明专利申请号:201210445091.0,申请日期:2012118日,申请人:东华大学。发明专利公开号:CN102920531A,公开日:2013213日。
  13. 王璐、沈高天、关国平、王富军、金马汀。一种管状纤维基人造血管涂层/接枝装置及使用方法。发明专利申请号: 201310459942.1,申请日期:2013927日。申请人:东华大学。发明专利公开号:CN 103498308A,公开日:2014 01 08

专著

  • 参编《生物医用纺织品》第2 医用纺织品的生物学基础,主编 王璐,Martin W KING201111月,北京:中国纺织出版社,ISBN: 978-7-5064-7889-2
  • 参编十二五规划教材《生物医用纺织品功能设计与制备》、《生物医用纺织品测试与评价》及《生物医用纺织品实验教程》,待出版。

国内外交流与合作

  1. Guoping Guan, Lu Wang, Mingzhong Li and Lun Bai, In vivo biodegradation of porous silk fibroin films implanted under the skin and muscle of the rat, The 2nd International Conference on Biomedical Engineering and Biotechnology (iCBEB 2013), 11-13 Oct. 2013, Wuhan.
  2. Guoping Guan, Md. Fazley Elahi, Lu Wang*, Gaotian Shen, Xiaohui Chen, Hao Zhou, Rui Xu, Promoted Cytocompatibility of Silk Fibroin Fiber Vascular Graft through Chemical Grafting with Bioactive Molecules, MedTex13, North Carolina State University, North Carolina State, US, May 13-15 2013
  3. Guoping Guan, Lu Wang, Xiaoyuan Yang, Quan Zhan, Lei Peng and Martin W. King. Fabrication and Biocompatibility Assessment of Woven Silk Fibroin and Polyester (PET) Small Diameter Prototype Vascular Prostheses. the 9th World Biomaterials Congress (WBC), June 1-5, 2012, Chengdu, China(Accepted)
  4. Guoping GUAN, Lu WANG, Quan ZHAN, Xiaoyuan YANG, Yuling LI, Robert GUIDOIN, Martin W. KING, Cellular compatibility and hemocompatibility of a silk fibroin-PET based small diameter vascular graft, International Conference on Fibrous Products in Medical and Health Care(FiberMed11), Tampere, Finland, June 28-30, 2011, oral presentation.
  5. GUAN Guoping, YANG Xiaoyuan, ZHAN Quan, WANG Lu, LI Yuling, WANG Fujun, Robert Guidoin, Martin W. KING, A Novel Silk Fibroin and PET Blended Textile for Small Diameter Vascular Graft, The Textile Institute Centenary World Conference Textiles: a Global Vision, 3 & 4 November 2010, Manchester, UK, Oral presentation;
  6. Guoping Guan, Lun Bai, Baoqi Zuo, Mingzhong Li, Zhengyu Wu, Lu Wang, Yonglin Li, Distinct Tissue Responses to Porous Silk Fibroin Scaffolds (PSFSs) and Polyvinyl Alcohol (PVA) Sponges in vivo, The 3rd International Conference on BioMedical Engineering and Informatics (BMEI 2010) and the 3rd International Congress on Image and Signal Processing (CISP 2010), 16-18 October 2010, Yantai, China, Oral presentation;
  7. 关国平, 许建梅, 詹葵华, 戴宏钦, 孙自玲, 左保齐, 李明忠, 王富军, 王璐, 白伦, 一种评价生物材料体内降解速率的方法,2010 CCBM-全国生物材料大会, 415-18日,成都,口头报告;
  8. Guan Guo Ping, Bai Lun, Xu Jian Mei, Zhan Kui Hua, Dai Hong Qin, Sun Zi Ling, A Semi-quantitive Method for Evaluating Degradation Rate of Degradable Biomaterials, The 2nd China-Europe Symposium on Biomaterials in Regenerative Medicine, 16-20th November 2009, Barcelona, Palau de la Música Catalana, el Petit Palau, Accepted as poster;
  9. Guoping Guan, Lun Bai, Baoqi Zuo, Mingzhong Li, Zhengyu Wu, Yonglin Li, Scaffolds Decorated by in vivo Environment Improve Cell Proliferation and Wound Healing, The 2nd International Conference on BioMedical Engineering and Informatics, 17-19 October 2009, Tianjin, China, Oral presentation;
  10. Guoping Guan, Lun Bai, Baoqi Zuo, Mingzhong Li, Zhengyu Wu, Yonglin Li, Distinct tissue responses to porous silk fibroin scaffolds (PSFSs) and polyvinyl alcohol (PVA) sponges in vivo, The 5th International Conference on Materials for Advanced Technologies (ICMAT 2009) and International Union of Materials Research Societies - International Conference in Asia (IUMRS-ICA 2009), 28 June-3 July 2009, Singapore, Oral representation;
  11. 关国平, 李明忠, 左保齐, 吴徵宇, 李永林, 白伦, 丝素蛋白基人工皮肤修复大鼠缺损真皮的效果观察, 第六届全国创伤修复与组织再生会议,200810月,口头报告,获得优秀论文奖;
  12. Guoping GUAN, Lun BAI, Baoqi ZUO, Mingzhong LI, Zilin SUN, Zhengyu WU, Neovascularization of Porous Silk Fibroin Films (PSFFs) as Dermis Substitutes Implanted in Rats, MRS International Materials Research Conference, 2008.06, Chongqing. Oral presentation;
  13. International Forum on Textile Science and Engineering for Doctoral Candidates, 2006.11, Donghua University, Shanghai.

联系信息

电话:67792686

Email: ggp@dhu.edu.cn