De-Qun Wu
发布时间： 2015-03-11

Name：De-Qun Wu

Title：Associate Professor

Tel：+86-21-6779-2380

Office：School of Textile, 4044

Email:dqwu@dhu.edu.cn

Background

  • 2004- 2009, Master and Ph.D, Department of Chemistry, Wuhan University, China
  • 2009, Postdoctoral Associate, Nanyang Technological University, Singapore
  • 2010- 2013, Postdoctoral Associate, Cornell University, USA.
  • 2013- Associate Professor, Donghua University, Shanghai, China

Researching Field

  1. Biomedical and textile materials
  2. Natural fiber modification
  3. Assembly of biodegradable materials and controlled drug carriers
  4. Nanomaterials based sensor

Awards

  • 2014 Shanghai Pujiang Program, 14PJ1400300
  • 2014 Textile Industry Federation First Prize for scientific and technological progress

Researching Project within five years

  2014 Shanghai Pujiang Program, 14PJ1400300

Papers & Patents within five years

Papers

1. Wu DQ, Sun YX, Xu XD, Cheng SX, ZhangXZ, and Zhuo RX. Biodegradable and pH-sensitive hydrogels for cell encapsulation and controlled drug release. Biomacromolecules 2008,9:1155-1162.

2. Wu DQ, Wang T, Lu B, Xu XD, Cheng SX, Jiang XJ, ZhangXZ, Ren-Xi Zhuo. Fabrication of supramolecular hydrogels for drug delivery and stem cell encapsulation. Langmuir 2008,24:10306-10312.

3. Wu DQ, Lu B, Chang C, Chen CS, Zhang YY, Cheng SX, Zhang XZ, Zhuo RX. Galactosylated fluorescent labeled micelles as a liver targeting drug carrier. Biomaterials. 2009,30:1363-1371.

4. Wu DQ, Qiu F, Wang T, Zhang XZ, Zhuo RX. Towards development of partially biodegradable and injectable thermoresponsive hydrogels for potential biomedical applications. ACS Applied materials & interfaces. 2009,1:319-327.

5. Wu DQ, Li ZY, Fan JJ, Cheng SX, Jiang XJ, ZhangXZ, Ren-Xi Zhuo. Porphyrin and Galactosyl Conjugated Micelles for Targeting Photodynamic Therapy. Pharmaceutical Research, 2010, 27:187-199.

6. Dequn Wu, Jun Wu, Chi-Chang Chu. A Novel Family of Biodegradable Hybrid Hydrogels from Arginine-based Poly(ester amide) and Hyaluronic Acid Precursors. Soft matter. 2013, DOI: 10.1039/c3sm27820d.

7. Jun Wu, Dequn Wu, Martha A. Mutschler, and Chih-Chang Chu, Cationic Hybrid Hydrogels from Amino Acid-Based Poly (ester amide): Fabrication, Characterization, and Biological Property.Advanced Functional Materials. 2012,22,3815-3823.

8. Xiao-Hong Qin, De-Qun Wu, Chih-Chang Chu. Dual functions of polyvinyl alcohol (PVA): fabricating particles and electrospinningnanofibers applied in controlled drug release. Journal of Nanoparticle Research. 2013,15:1395-1409.

9.Lu B,Wu DQ,Zheng H,Quan CY,Zhang XZ, Zhuo RX.Galactosyl conjugated N-succinyl-chitosan-graft-polyethylenimine for targeting gene transfer.Molecular Biosystems, 2010, 6, 2529-2538.

10.Xun W, Wu DQ, Li ZY, Wang HY, Huang FW, Cheng SX, Zhang XZ, ZhuoRX.Peptide-Functionalized Thermo-Sensitive Hydrogels for Sustained Drug Delivery. Macromolecular bioscience. 2009, 12, 1219-1226.

11. Quan CY, Wu DQ, Chang C, Zhang GB, ChengSX, Zhang XZ, Zhuo RX. Synthesis of thermo-sensitive micellar aggregates self-assembled from biotinylated PNAS-b-PNIPAAm-b-PCL triblock copolymers for tumor targeting. Journal of Physical Chemistry C. 2009, 113:11262-11267.

12. Wang T, Wu DQ, Jiang XJ, Li XY, Zhang JF, Zheng ZB, Jiang H, Huang CX, Zhang XZ. Novel thermosensitive hydrogel injection inhibits post-infarct ventricle remodeling. European Journal of Heart Failure. 2009, 11:14-19.

13. Lu B, Wang CF, Wu DQ, Li C, Zhang XZ, Zhuo RX. Chitosan based oligoamine polymers: synthesis, characterization, and gene delivery. Journal of Controlled Release. 2009,137:54-62。

14. Hu CH, Zhang L, Wu DQ, Cheng SX , Zhang XZ, Zhuo RX. Heparin-modified PEI encapsulated in thermosensitive hydrogels for efficient gene delivery and expression. Journal of materials chemistry. 2009,19:3189-3197.

15. Qin XH, Wu DQ. Effect of different solvents on poly(caprolactone) (PCL)electrospun nonwoven membranes. Journal of Thermal Analysis andCalorimetry, 2011, 102, 1-7.

16. Chang C, Wei H, Feng J, Wang ZC, Wu XJ, Wu DQ, Cheng SX, Zhang XZ, and ZhuoRX.Temperature and pH Double Responsive Hybrid Cross-Linked Micelles Based on P(NIPAAm-co-MPMA)-b-P(DEA): RAFT Synthesis and “Schizophrenic” Micellization. Macromolecules 2009,42:4838-4844.

17. Zhang J, Xu XD, Wu DQ, Zhang XZ, Zhuo RX. Synthesis of thermosensitiveP(NIPAAm-co-HEMA)/cellulose hydrogels via “click” chemistry. Carbohydrate Polymers. 2009,77:583–589.

18. Qiu F, Feng J, Wu DQ, Zhang XZ, Zhuo RX. Nanosized Micelles Self-Assembled from amphiphilic dextran-graft-methoxypolyethylene glycol/poly(epsilon-caprolactone) copolymers. European Polymer Journal. 2009, 45:1024-1031.

19. Wang T, Jiang XJ, Tang QZ, Li XY, Lin T, Wu DQ, Zhang XZ, Okello E. Bone marrow stem cells implantation with a-cyclodextrin/MPEG–PCL–MPEG hydrogel improves cardiac function after myocardial infarction. ActaBiomaterialia. 2009, 5: 2939-2944.

20. Wei H, Wu DQ, Li Q, Cheng SX, ZhangXZ, and Zhuo RX. Preparation of shell cross-linked thermoresponsive hybrid micelles as well as hollow spheres based on P(NIPAAm-co-HMAAm-co-MPMA)-b-PCL. Journal of physical chemistry C. 2008, 112:15329.

21. Qin XH, Wu DQ. Effect of different solvents on poly(caprolactone) (PCL)electrospun nonwoven membranes. Journal of Thermal Analysis andCalorimetry, 2011, 102, 1-7.

22. Li XY, Wang T, Jiang XJ, Lin T, Wu DQ, Zhang XZ. Injectable Hydrogel Helps Bone Marrow-Derived Mononuclear Cells Restore Infarcted Myocardium. Cardiology. 2010, 115,194-199.

23. Wang T, Jiang XJ, Tang QZ, Li XY, Lin T, Wu DQ, Zhang XZ, Okello E. Bone marrow stem cells implantation with a-cyclodextrin/MPEG–PCL–MPEG hydrogel improves cardiac function after myocardial infarction. ActaBiomaterialia. 2009, 5: 2939-2944.

24.Jun Wu, Xin Zhao, Dequn Wu and Chih-Chang Chu.Development of a biocompatible and biodegradable hybrid hydrogel platform for sustained release of ionic drugs.J. Mater. Chem. B, 2014,2, 6660-6668.

Patent

Chinese Patent:

    Xian-zheng Zhang, De-qun Wu, Ren-Xi Zhuo. Preparation and application of biodegradable and temperature sensitive hydrogel. Application number: 200810048486.0

US Patent:

1. Chu Chih-Chang, Wu De-Qun. Advanced Generation Lysine-based Multifunctional Poly(ester amide)s. D-5447

2.Chu Chih-Chang, Wu De-Qun. Peptide-based Poly(ester amide)s D-5400

3. Chu Chih-Chang, Wu De-Qun, He Mingyu. Polysaccharide-based hydrogels and hybrid hydrogels and precursors thereof, methods of making same, and uses thereof. Publication number: WO2013/181566

4. Chu Chih-Chang, Qin Xiao-Hong, Wu De-Qun. Fabrication of SyntheticBiodegradable Amino Acid Poly(ester amide)s Nanoparticles . D-5597